NOVA scienceNOW : 4 - Profile : Naomi Halas

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ROBERT KRULWICH: Okay, enough of big, time to get small again. And I mean really, really

small. Here's something exquisitely small. This is the tip of a pin. We're going to move

in on the tip and get smaller still.

You see those little blobs there? They are bacteria on the pin, and then on the bacteria,

you see that little speck? It's a few hundred atoms across.

That teeny thing made news recently, because it is an invention. It was built by a scientist

you're about to meet. And the fact that she is a she was also news, because there aren't

a lot of shes doing this kind of thing. And some prominent folks have wondered why. So

here is her story.

Naomi Halas knows how guys think. Her ranch in Texas is way, way outside Houston in brush

country, so it's a little hard to find, but, as it happens...

NAOMI HALAS: One of our neighbors used to be a, was a former Penthouse Pet, so she was

a bit of a local celebrity.

ROBERT KRULWICH: So whenever Naomi needed lumber, or whatever, delivered, all she had

to say to the delivery guy, any delivery guy apparently, was...

NAOMI HALAS: "Do you know where the stripper lives?" And they would all know. And so rather

than going into long detailed directions, all I'd have to do is say well, we're about

200 yards past the stripper, on the left.

ROBERT KRULWICH: The ranch is for weekends. During the week, Naomi Halas is a professor

at Rice University teaching Nanotechnology and Applied Physics, fields that are 90 percent

dominated by men. But not here. Not in her group. If you look around, it's about even,

which is different for guys...

SWEDISH GRAD STUDENT: I think this is great. What else could I say?

ROBERT KRULWICH: ...and very different for women.

STUDENT: Being a woman has actually never been an issue for me in this group. You just

forget about it, which is nice, a nice feeling, because a lot of people aren't that lucky.

ROBERT KRULWICH: So how'd this happen? How'd Naomi create such an unusual balance? Even

her husbandóthis is Peteróhe joins the group, not as the leader, he's just one of the gang.

Well, there's a story here.

NAOMI HALAS: You know, the best science stories are told backwards, okay? So...

ROBERT KRULWICH: So let's go back a bit. When Naomi was growing upóyeah that's her, and

so is thisóshe never thought about becoming a scientist, even in high school.

NAOMI HALAS: I remember very clearly in high school, although I was always at the top of

my class in math and science, I was told, "Don't take physics." And the reason I was

told not to take physics was because if I ever took physics, I would never get a date.

ROBERT KRULWICH: So she didn't take physics, she became a musician. And one day, she was

wondering where sounds came from, and a friend said, "Well, acoustics requires calculus."

NAOMI HALAS: "But, of course, you've taken calculus, haven't you?" And it just kind of

hit me like a load of bricks. In fact, I hadn't taken calculus. I had actually bought into

this myth that maybe I probably wasn't going to be very good at math.

ROBERT KRULWICH: But she was good. So at 20, she decided, "You know what? I'm going to

drop music and switch to something science-y."

NAOMI HALAS: I thought, "Well, maybe I want to retool my career."

ROBERT KRULWICH: But what about her, you know, her uh, feminine problem?

NAOMI HALAS: No, I didn't, I didn't have a feminine problem.

ROBERT KRULWICH: In other words, you weren't embarrassed to do un-girlish stuff?

NAOMI HALAS: No, I was really a...I was really butch, actually.

ROBERT KRULWICH: So she switched from music to chemistry, and then, interestingly, chose

a female-friendly graduate program at Bryn Mawr.

NAOMI HALAS: Bryn Mawr was certainly a place where women were 100 percent accepted.

ROBERT KRULWICH: And that's where she got her M.A. and Ph.D. in physics, and she married.

NAOMI HALAS: Have you thought about doing that?

ROBERT KRULWICH: And when she joined the faculty at Rice University, Naomi found herself increasingly

attracted by the world of the very, very small, the nano world.

NAOMI HALAS: This is a vial of gold nano particles, solid gold nanospheres.

ROBERT KRULWICH: They're so small you can't see them. They're little clumps of gold atoms.

But if you invent a clump that's hollow inside it will absorb a different color of light.

And by changing the thickness of the gold shell, you can make it absorb whatever color

you want. So look. Here, what was once ruby red is now clear.

Naomi's work was new and very interesting to graduate students, well to men. Women...?

NAOMI HALAS: For the first six years, I had no women whatsoever. And then I had one. And

once, once I had her, I became okay, and then lots of women began to join my group.

ROBERT KRULWICH: Which was, at first, kind of unusual.

GRADUATE STUDENT: We're changing that. It won't be unusual for long.

ROBERT KRULWICH: Women told women, "This is a good group." Naomi says, "You know, I never

planned this."

NAOMI HALAS: It just seems to sort of happen. Maybe having all these women attracts the

men.

ROBERT KRULWICH: So in the end, she gets a balance. But the growing gang of women at

Rice were at first, invisible.

NAOMI HALAS: For most of my scientific career I didn't publish with my first name in the

paper. I was always N. Halas. And so, many people knew about my work and had no idea

I was a woman, because they read my work in the literature.

ROBERT KRULWICH: But when Naomi and her colleagues created nanoshells by manipulating atoms,

then the world noticed: The New York Times, Popular Science, Profiles. Nanoshells made

Naomi and her lab famous. And yet, even as a tenured professor, plus by now she'd bought

the ranch. As successful as she was, one day when she was presenting her findings at a

meeting at Rice...

NAOMI HALAS: A man walked up to me, and in a very loud voice, said, "Excuse me, are you

the lady in charge of the coffee?" And when I heard that, I just turned around and I walked

back to my office, and I just sat there and, you know, I almost burst into tears. This

is ridiculous. I don't want to have...Is it for the rest of my life, I'm going to be mistaken

for somebody who's in charge of the coffee? And then I said, "No, I think I will go back

there because I don't want that person to win. I want to, I want to be, I want to participate

in the forum and I don't care if he thinks I'm in charge of the coffee." So I went back.

ROBERT KRULWICH: And the contacts she made at that meeting led to a business, which she

started with biology professor Jennifer West. And they are now injecting nanoshells into

animals with cancer. So here, to demonstrate, they're using a chicken breast. The nanoshells

will gather inside the tumor.

NAOMI HALAS: And once they're in place, then light is shined through the skin and down

into the tumor site.

ROBERT KRULWICH: ...warming up the nanoshells so they burn the tumor. That's the steam there.

NAOMI HALAS: And that's sufficient to kill the cells in the tumor.

ROBERT KRULWICH: So without radiation, with light, you can attack cancer sites.

NAOMI HALAS: That's incredibly non-invasive, if you consider other types of cancer therapies.

ROBERT KRULWICH: These therapies are still being tested by the women and the men who

have gathered around Naomi. But the women, she says, even now, have to struggle to stay

in the game.

NAOMI HALAS: I always thought it was a generational thing. I always thought, well when I was a

young scientist, "Oh, those are the older people. They're like that. But when people,

when I'm older, then people won't be like that anymore." But they are.

ROBERT KRULWICH: Too often, female grad students drop out, lose confidence, struggle to balance

children and family. Naomi, I noticed, does not have children, which made me wonder if

that's about work.

NAOMI HALAS: No, I cannot have children.

ROBERT KRULWICH: Oh.

NAOMI HALAS: So it's not that we didn't try. I am absolutely...I mean, that's another thing

that people do sometimes, look at someone who is childless and say, "Well, you know,

she...you know, you like science more than, you know, children and flowers and, you know,

things like that," you know? But no, I like kids too.

ROBERT KRULWICH: But what she doesn't like is that half the kids, all the girls, still

have trouble making the life that she has made. That struggle isn't over.